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Lihlahisoa

Adenosine

Tlhaloso e Khutšoanyane:

Lebitso: Adenosine
Nomoro ea CAS: 58-61-7
Nomoro ea ho kena ea EINECS: 200-389-9
Mokhoa oa molek'hule: C10H13N5O4
Boima ba molek'hule: 267.25


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Foromo ea Sebopeho

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Ea nama

Ponahalo: kristale e tšoeu kapa phofo e tšoeu ea kristale
Boima: 2.08 g/cm³
Sebaka se qhibilihang: 234 ho isa ho 236 ℃
Sebaka se belang: 676.3 ℃
Refractivity: 1.907
Sebaka se phatsimang: 362.8 ℃

Lintlha tsa Polokeho
Sehlopha se kotsi.
Nomoro ea Lipalangoang tsa Thepa e Kotsi.
Sehlopha sa ho paka.

Kopo
Adenosine e sebelisoa ho thusa ho tsosolosa ho otla ha pelo ho tloaelehileng ho batho ba nang le mathata a itseng a pelo.
Adenosine e boetse e sebelisoa nakong ea teko ea khatello ea kelello ea pelo.
Adenosine e ka boela ea sebelisoa molemong oa merero e sa thathamisitsoeng bukeng ena ea meriana.

Adenosine, motsoako o nang le N-9 ea adenine e amanang le C-1 ea D-ribose ka tlamo ea β-glycosidic, e na le mokhoa oa lik'hemik'hale C10H13N5O4 le phosphate ester ea eona ke adenosine acid.Adenosine ke endogenous nucleoside hore namela ho pholletsa le lisele tsa motho le ka ka ho toba kena myocardium ho hlahisa adenosine acid e ka phosphorylation, e amehang myocardial matla metabolism, hammoho le ho dilating methapo ea mali le ho eketsa phallo ea mali.E sebelisoa ho phekola tachycardia ea supraventricular.Adenosine e na le litlamorao tsa 'mele tsamaisong ea pelo le litsamaiso tse ling tse ngata le lisele tsa mesifa.Adenosine ke karolo ea bohlokoa ea bohareng e sebelisoang ho kopantseng adenosine triphosphate (ATP), adenine, adenosine acid, le adenosine asiaticum.
Hape ke moemeli oa antiarrhythmic o fetolang paroxysmal supraventricular tachycardia ho sinus rhythm.E sebelisoa bakeng sa arrhythmias ea supraventricular e amanang le atrioventricular.Kalafo ea angina pectoris, myocardial infarction, coronary insufficiency, atherosclerosis, khatello ea kelello ea bohlokoa, mafu a cerebrovascular, sequelae post-stroke, atrophy ea mesifa e tsoelang pele, joalo-joalo E boetse e sebelisoa lithutong tsa biochemical.
Adenosine ke endogenous purine nucleoside e liehisang AV node conduction, thibela AV nodal fold pathway, le ho tsosolosa tloaelo ea sinus rhythm ho bakuli ba paroxysmal supraventricular tachycardia (PSVT) (ka kapa ntle le preexcitation syndrome).Adenosine e nkoa ka potlako ke lisele tse khubelu tsa mali 'me ka hona e na le nako e khutšoanyane ea ketso, e nang le halofo ea bophelo ea plasma e ka tlase ho 10 s.Mofuta o tloaelehileng ka ho fetisisa oa PSVT ke ka tsela ea ho khutlela morao, kahoo adenosine e atleha ho felisa mofuta ona oa arrhythmia.Ho non-atrial kapa sinus node regressive arrhythmias (mohlala, atrial flutter, atrial fibrillation, atrial tachycardia, ventricular tachycardia), adenosine ha e li felise, empa e ka hlahisa block ea nakoana ea atrioventricular kapa ventricular, e ka thusang ho etsa tlhahlobo e fapaneng.


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