P-Nitroacetophenone

Tlhaloso e Khutšoanyane:

Li-intermediate tsa organic synthesis le pharmaceutical synthesis (joalo ka synthomycin, chloramphenicol).E boetse e sebelisoa ha ho etsoa chefo e bolaeang likokoanyana, dae le linoko.

Re romelle lengolo-tsoibila

Lintlha tsa Sehlahisoa

Li-tag tsa Sehlahisoa

Lintlha tsa Sehlahisoa

CAS NO: 100-19-6

Bohloeki: ≥99%

Mokhoa: C8H7NO3

Foromo ea Wt: 165.15

Lebitso la lik'hemik'hale: 4-Nitroacetophenone;

4'-Nitroacetophenone;p-Nitroacetophenone

Lebitso la IUPAC: 1-(4-nitrophenyl)thanone;

Ethanone, 1-(4-nitrophenyl)-

Sebaka se qhibilihang: 75-78°C

Sebaka se belang: 202°C

Sebaka sa Flash: 201-202°C

Ponahalo: Prism e mosehla kapa phofo e khanyang e mosehla

Thomello le Polokelo

Mocheso oa Lebenkele: Mocheso oa Kamore

P-nitroacetophenone ke karolo ea bohlokoa ea lipakeng ho organic synthesis 'me e sebelisoa e le thepa e tala bakeng sa motsoako oa chlortetracycline le chloramphenicol meriana.Mokhoa o tloaelehileng oa tlhahiso ea indasteri ea p-nitroacetophenone ke oxidation ea ethylbenzene.Ntle le sehlahisoa se seholo sa p-nitroacetophenone, ho na le lihlahisoa tse kang p-nitrobenzoic acid tsamaisong ea karabelo.Metsi a litšila a hlahisoang a na le litšobotsi tse latelang: ① khatello e phahameng, acidity e matla, 'mala o lefifi le chefo e phahameng;② sebopeho sa motsoako ka metsing a litšila se tsitsitse ebile ha se bonolo ho senyeha, kahoo mekhoa e akaretsang e kang activated carbon adsorption, electrolysis le precipitation e ke ke ea finyella phello e lakatsehang.Resin adsorbent e na le adsorption e matla le bokhoni ba ho nchafatsa, 'me thepa ea eona ea' mele le ea lik'hemik'hale e tsitsitse ebile e ka sebelisoa khafetsa.
Thepa
Sehlahisoa se hloekileng ke kristale e mosehla kapa kristale ea nale.Sebaka se qhibilihang ke 80℃82℃.Sebaka se belang 202 ℃.E qhibiliha ka bolokolohi ka har'a ethanol e chesang, ether le benzene, e sa qhibiliheng metsing.
Tokisetso
Ethylbenzene e tšeloa ka asiti e tsoakiloeng ho 30～35℃ ho fumana nitroethylbenzene.Ka mor'a distillation, p-nitroethylbenzene le co-product o-nitroethylbenzene li fumanoa.Boteng ba catalyst cobalt stearate, p-nitroethylbenzene e oxidized ka moea ho 140-150 ℃ le 0.2MPa khatello ea ho fumana p-nitroacetophenone.Sehlahisoa sa karabelo se ne se hlatsuoa ka metsi, se sa nke lehlakore, se centrifuged le ho felloa ke metsi, 'me se omisitsoe ho fana ka sehlahisoa se felileng.
mokhoa oa p-Nitrobenzoyl chloride.
Polokeho
Chefo ha e tsejoe.Thepa ea tlhahiso e lokela ho se kenele moea 'me mokhanni a roale lisebelisoa tse sireletsang.
E phuthetsoe ka meqomong ea tšepe kapa meqomong ea lepolanka e kentsoeng ka mekotla ea polasetiki.Boloka sebakeng se omileng le se nang le moea oa moea.