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Indole-3-methanol

Tlhaloso e Khutšoanyane:

Indole-3-methanol ke semela se secha sa metabolite se hlahisoang ka meroho ea cruciferous, e ka ntšoang meroho ea cruciferous (e kang broccoli, radish le cauliflower).Indole-3-carbinol ke sesebelisoa sa chemopreventive ea tumor.Indole-3-carbinol e ka thibela ketsahalo le nts'etsopele ea lihlahala tse fapaneng.Indole-3-methanol e ne e sebelisetsoa ho kenyelletsa poly lactic acid co glycolic acid (PLGA) ho ithuta phello ea eona ea anticancer ho matsoele adenocarcinoma epithelial cells (MCF7), colon adenocarcinoma epithelial cells (Caco2) le prostate cancer epithelial cells (PC3) in vitro.E boetse e sebelisoa e le inducer ea cytochrome P4501A (CYP1A).

Lintlha tsa Sehlahisoa

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Tlhaloso

Indole-3-methanol (I3C) e kenya tšebetsong receptor e nkhang hamonate ea hydrocarbon (AHR) mme e etsa hore ho ts'oaroe ha lisele tsa G1 le apoptosis.Ka hona, ke moemeli oa anticancer o ka bang teng.Ho feta moo, e etsa hore estradiol metabolism e be e susumetsang cytochrome P450 enzyme.Ka hona, I3C e nkoa e le sethethefatsi se sebetsang sa chemotherapy bakeng sa mefuta e fapaneng ea mofets'e, ho kenyeletsoa mofetše oa matsoele, mofetše oa prostate, mofets'e oa colon le leukemia.Indole-3-methanol e ka susumetsa feela ho hlaha ha lisele tsa mofets'e, tse bolokehileng ebile li se na cytotoxic ho lisele tse se nang tumor.Ka lebaka la ts'ebetso ea eona e phahameng, e se nang chefo le thepa ea tlhaho e khahlanong le hlahala, indole-3-methanol e ka sebelisoa e le e 'ngoe ea likhetho bakeng sa litlhare tsa thibelo le kalafo ea mofets'e.

Lintlha tsa Sehlahisoa

Cas No.: 700-06-1

Bohloeki: ≥98%

Tlhaloso: C9H9NO

Foromo ea Wt.Tlhaloso: 147.17

Lebitso la lik'hemik'hale: INDOLE-3-CARBINOL

Synonym: Indole-3-carbinol, 99.5%; Indole-3-carbinol98%;(1H-Indol-3-yl)-methano;Indol-3-yl-methanol;3-INDOLAMETHChemicalbookANOL;INDOLE-3-CARBINOL: 3-INDOLEMETHANOL;INDOLE-3-CARBINOL(RG);3-HYDROXYMETHYLINDOLE(INDOLE-3-CARBINOL)

Sebaka se qhibilihang: 96-99 °C

Sebaka se belang: 267.28°C

Ponahalo: E soeufetse ho isa ho phofshoana e mosehla oa lamunu kapa li-flakes

Thomello le Polokelo

Botsitso ba polokelo Bo khothalelitsoeng mocheso oa polokelo 2 - 8 °C.

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